Recent Publications

McKitterick AC, Hays SG, Johura FT, Alam M and Seed KD. 2019. Viral satellites exploit phage proteins to escape degradation of the bacterial host chromosome. BioRxiv 671271 [Preprint]. June 14, 2019.

Barth ZK, Silvas TV, Angermeyer A and Seed KD. 2019. Genome replication dynamics of a bacteriophage and its satellite reveal strategies for parasitism and viral restriction. BioRxiv 639039 [Preprint]. May 17, 2019.

McKitterick AC, LeGault KN, Angermeyer A, Alam M and Seed, KD. 2019. Competition between mobile genetic elements drives optimization of a phage-encoded CRISPR-Cas system: Insights from a natural arms-race. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 374:20180089. (Link)

Angermeyer A, Das MM, Singh DV and Seed KD. 2018. Analysis of 19 highly conserved Vibrio cholerae bacteriophages isolated from environmental and patient sources over a twelve-year period. Viruses. 10:299. (Link)

McKitterick AC and Seed KD. 2018. Anti-phage islands force their target phage to directly mediate island excision and spread. Nature Communications. 9:2348. (Link)

O’Hara BJ, Barth ZK, McKitterick AC and Seed KD. 2017.  A highly specific phage defense system is a conserved feature of the Vibrio cholerae mobilome. PLOS Genetics. 13: e1006838. (Link)

Box AM, McGuffie MJ, O’Hara BJ and Seed KD. 2016. Functional analysis of bacteriophage immunity through a type I-E CRISPR-Cas system in Vibrio cholerae and its application in bacteriophage genome engineering. Journal of Bacteriology. 198:578–590. (Link)

Dalia AB, Seed KD, Calderwood SB and Camilli A. 2015. A globally distributed mobile genetic element inhibits natural transformation of Vibrio choleraePNAS. 112:10485-90. (Link)

Seed KD. 2014. Battling phages: how bacteria defend against viral attack. PLoS Pathogens. 11(6):e1004847. (Link)

Seed KD, Yen M, Shapiro BJ, Hilaire IJ, Charles RC, Teng JE, Ivers LC, Boncy J, Harris JB and Camill A. 2014. Evolutionary consequences of intra-patient phage predation on microbial populations. eLife. 3:e03497. (Link)

     Notable Media coverage:

  • Research Highlight: Molloy S. 2014. In-house dining for phage. Nature Reviews Microbiology. 12 : 658. (Link)

Seed KD, Lazinski DW, Calderwood SB and Camill A. 2013. A bacteriophage encodes its own CRISPR/Cas adaptive response to evade host innate immunity. Nature. 494:489-491. (Link) 

     Notable Media coverage:

  • News and Views: Villion M and Moineau S. 2013. Virology: Phages hijack a host’s defence. Nature. 494:433-434. (Link)

  • Research Highlight: Kåhrström CT. 2013. Phages level the playing field. Nature Reviews Microbiology. 11: 300-301. (Link)

  • News article: A Virus That Steals A Bacterium’s Immune System And Uses It As A Weapon. Popular Science, March 4, 2013. (Link)

  • News article: The virus that learns. National Geographic Phenomena Blog, February 27, 2013. (Link)

Seed KD, Faruque SM, Mekalanos JJ, Calderwood SB, Qadri F and Camilli A. 2012. Phase variable O antigen biosynthetic genes control expression of the major protective antigen and bacteriophage receptor in Vibrio cholerae O1. PLoS Pathogens. 8:e1002917. (Link)

Seed KD, Bodi KL, Kropinski AM, Ackermann HW, Calderwood SB, Qadri F and Camilli A. 2011. Evidence of a dominant lineage of Vibrio cholerae-specific lytic bacteriophages shed by cholera patients over a 10-year period in Dhaka, Bangladesh. mBio. 2:e00334-10.(Link)

Complete list of publications generated by PubMed